• research on the influence of drugs and new compounds on the cardiovascular system, urinary system, metabolic disorders, including obesity;
• biofunctional tests, on various isolated organs;
• research on safety pharmacology and monitoring of adverse events.

• a system for telemetry monitoring of blood pressure, ECG, temperature, and spontaneous activity in small animals;
• set for measuring the spontaneous activity of animals that may be present in herds in cages home;
• apparatus for nonstress monitoring of temperature and heart rate in rats;
• set for measuring the effect on isolated organs (including heart);
• cardiomonitor with the possibility of measuring oxygen saturation;
• apparatus for measuring blood pressure with direct or indirect method.

• determination of action of  new compounds in circulatory systems. Effects on blood pressure and / or heart - in vivo, in vitro and ex vivo studies in laboratory animals;
• determination of the intrinsic activity of the new compounds as compared to the adrenergic, serotoninergic, dopaminergic, adenosine and histamine receptors.
• research in the field of safety pharmacology of the novel compounds;
• indications of acute toxicity and local toxicity in different species, in different routes of administration;
• indications of possible adverse effects of new compounds;
• the biofunctional tests of impact of new compounds on various isolated organs;
• various biochemical tests, e.g.: determination the effect of the compounds on lipid and carbohydrate profile; plasma levels of various substances and enzymes activity;
• planning and implementation of a variety of research in experimental pharmacology;
• performing research in the field of safety pharmacology;
• indications of possible adverse effects of new compounds, medicinal products, medical devices, drugs;
• determinations of intrinsic activity of ligands to different receptors in vitro;
• making bio-functional studies using isolated organ bath;
• indications of acute toxicity and local irritative activity;
• preparation of Common Technical Document for the Registration of Pharmaceuticals for Human Use;
• performing a variety of biochemical assays.

Methods and research techniques:

• system to telemetric blood pressure, ECG, temperature and spontaneous activity monitoring - animals are not subjected to the stress of isolation during research;
• the innovative system for measuring the spontaneous activity of animals - possibility to monitor the activity of animals in natural conditions without chronic stress;
• the innovative system for measuring body temperature and heart rate in rats which enables measurement without any interference – lack of stress during each   measurement (multiple times per day);
• preliminary screening tests are performed in vitro: determination of the effect on the heart, the function of individual organs, biochemical tests.

• experience in contract research – cooperation with pharma companies: Adamed Group, Biomed, Apipol, Espefa.