• studies on interaction between selected proteins and inhibitors or other compounds of biological importance;
• studies on conformational changes associated with protein folding and structural changes in proteins under high pressure;
• examination of relationship between crystal structure and biological activity of small organic molecules (e.g. drug candidates).

• apparatus for synthesis, modification and purification of proteins;
• chromatographic system for biomolecules FPLC AKTA Purfier 10 (Ge Pharmacia);
• UV-vis spectrophotometer T80+ (PG Instruments Ltd);
• lyophilizer Alpha 1-2 LD plus (Christ);
• shaking incubator MaxQ 400 (ThermoScientific);
• water bath BM 302 (Nuve);
• shaking thermoblock MHR 11 (HLC);
• incubator CO2 Midi 40 (ThermScientific);
• refrigerated centrifuge Sorvall ST16R (ThermoScientific);
• microcentrifuge Espresso (ThermoScientific);
• laminar chamber MSC Advantage 1.2 (ThermoScientific);
• shaker type FineVortex i shaker cradle CR 300 (FinePCR);
• autoclave OT40L (Nuve);
• system for water purification Barnsted EASY Pure RoDi (ThermoScientific);
• distillation apparatus NS 112 (Nuve);
• mechanical homogenizer CAT X120;
• ultrasonic homogenizer Ultrasonic 50H (Hielscher Ultrasounds Technology);
• ultrasonic cleaner Elmasonic S10 (Elma);
• pH-meter LAB 850 SET (Schott Instruments);
• technical and analytical balance (Radwag);
• peristaltic pump SP Quick 1.6 (Heidolph);
• refrigerator Q-cell 140 Basic (Poll Lab);
• freezer ULTF 90 (drDAIRE);
• microwave (Bosh);
• apparatus for the vertical and horizontal electrophoresis of proteins and nucleic acids Mini-Protean Tetra Cell (BioRad).

• new biologically active molecules, drug candidates;
• ceramic-polymer composite implants for a carrier for drugs with potential application in craniofacial surgery;
• design, synthesis and structural studies of proteins and their complexes with biologically active substances.

Methods and research techniques:

• protein crystallization methods;
• chromatographic methods;
• spectroscopic methods;
• X-ray crystallography methods.