search contract research
Department of Pharmacokinetics and Physical Pharmacy, Faculty of Pharmacy Jagiellonian University CM
keywords: statistical analysis, pharmacokinetic, analytical methods
offer number: 88
research topics:
  • pharmacokinetic and pharmacokinetic-pharmacodynamic studies on new compounds;
  • assessment of pharmacokinetic drug interactions involving metabolism, drug transport and plasma protein binding;
  • investigation on the influence of some inflammatory disorders on pharmacokinetic profile of drugs in experimental disease models;
  • application of population modeling to optimization of pharmacotherapy;
  • application of  pharmacokinetic-pharmacodynamic modeling to data analysis and simulations;
test equipment:
  • HPLC with DAD, electrochemical and fluorimetric detection (Merck Hitachi, 2007, Japan)
  • organ perfusion system PS-1 (Hugo Sachs Elektronik - Harvard Apparatus, 2009, United Kingdom)
  • microdialysis system (CMA Microdialysis AB, 1999, Sweden)
  • Equilibrium dialysis system (Harvard Apparatus, 2011, United Kingdom)
  • Flow-through cell apparatus (Ismatec/Julabo , 2011, Germany) 
comercial research:
  • development and validation of analytical methods  for determination of new compounds in   different biological matrices (plasma, serum, urine, tissue homogenates);
  • assessment of pharmacokinetic profiles of new compounds and selection of compounds with the most favourable pharmacokinetic parameters for further development;
  • assessment of plasma protein binding  of new compounds;
  • evaluation of metabolism and transport of new compounds using isolated perfused organs;
  • selection of an appropriate dose for phase I clinical trials (allometric scaling);
  • measurement of markers of drug response and assessment of pharmacokinetic-pharmacodynamic relationships;
  • pharmacokinetic studies on new compounds – drug candidates performed according to FDA and EMA recommendations;
  • development and validation of analytical methods for determination of compounds in different biological matrices (serum, plasma, tissue homogenates, urine, feces) using HPLC with different types of detection according to FDA and ICH recommendations;
  •  Development and validation of enantioselective HPLC methods for racemic compounds;
  • determination of biomarkers of drug response and pharmacokinetic-pharmacodynamic modelling;
  • statistical analysis;
variants of cooperation: contract research, project, consortium
type of services: analysis, devices for rent, expertises

information / broker of Jagiellonian University

name and surname:
phone number: + 48 12 664 42 00
NEWS
latest information
JU scientists to develop biological agricultural support solutions
The project “Interactions between plants and microorganisms in response to the presence of potentially toxic metals, metalloids and silicon (Si)” by Prof. Katarzyna Turnau from the JU Faculty of Biology won a grant from the Polish National Agency for Academic Exchange. The study aimed at replacing the widespread use of agrochemicals with biological agricultural support solutions will also involve researchers from Slovakia and Austria.
JU students will help people suffering from depression
Therapify is a mobile application designed to help depressed people. It was first conceived by Łukasz Pstrong, a graduate of the AGH University of Science and Technology in Kraków, and developed over the course of the last two years with collaborators from his university, the Jagiellonian University, and SWPS University of Social Sciences and Humanities in Warsaw.
Plakaty Demo Day II +
In January, we complete the project managed by CTT CITTRU as part of the program of the Ministry of Science and Higher Education - Incubator of Innovation +. We supported, among others, 18 research teams selected in the competition, that develop innovative technologies. Thanks to the funds granted by CTT CITTRU and hard work of technology transfer officers, pre-implementation research was financed, which increased the attractiveness of these inventions and investors interest in them. Take look at the gallery of posters for technologies, developed as part of the project. What do you think about it
CITTRU team
Our employees
PARTNERS
Innovation Forum KrakówKlaster Lifescience KrakówWolves SummitPACTTJagiellońskie Centrum Innowacji
Contact
GET IN TOUCH WITH US
Centre for Technology Transfer CITTRU
Jagiellonian University in Kraków - POLAND
ul. Bobrzyńskiego 14,
30-348 Kraków

PHONE:
+48 12 664 42 00
E-MAIL:
cittru@uj.edu.pl
Fundusze EuropejskieMNiSWInkubator InnowacyjnościUnia Europejska