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Department of Technology and Biotechnology of Drugs Faculty of Pharmacy Jagiellonian University
keywords: biotechnology, drugs, cytotoxicity, genotoxicity, genetic engineering, mutagenic properties
offer number: 76
research topics: 
- Searching for chemical compounds with expected biological activities:
- having affinity to specific receptors
- having anticonvulsant, procognitive, antineurodegenerative, antiarrhythmic, hypotensive or antibacterial properties
- with properties increasing effectiveness of drugs (e.g. antibiotics and anticancer drugs)
- Analysis of physicochemical- and spatial properties of compounds with potential biological activity with theoretical and experimental methods
- Biotransformation of biologically active compounds with use of microorganisms and enzymes
- Synthesis of recombinant proteins using methods of genetic engineering
- Synthesis and application of monoclonal antibodies
- An evaluation of side effects of biologically active compounds, including genotoxicity and cytotoxicity
test equipment:
- spectrophotometry equipment
- systems for chromatography
- CEM Discovery Microwave Synthesis System
- bioreactor, biophotometer UV/VIS
- PCR thermocycler
- DNA and protein electrophoresis systems
- Laminar air flow cabinets
- absorbance and multimode microplate reader
comercial research:
- Synthesis of chemical compounds
- Synthesis of recombinant proteins
- An evaluation of cytotoxic-, mutagenic- and genotoxic properties of chemical compounds
- Biotransformation tests by the use of recombinant enzymes or whole (un)immobilized cells
variants of cooperation: contract research, project, consortium
type of services: analysis, devices for rent, expertises
information / broker of Jagiellonian University
name and surname:
phone number: + 48 12 664 42 00
email: cittru@uj.edu.pl
